Mouse Kcnq5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnq5
Locus ID	226922
Kit Components	GA213899G1, Kcnq5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213899G2, Kcnq5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213899G3, Kcnq5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001160139, NM_001310477, NM_023872
Synonyms	7730402H11; 9230107O05Rik; AA589396; D1Mgi1
Summary	Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current.[UniProtKB/Swiss-Prot Function]

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