Mouse Tdrd5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tdrd5
Locus ID	214575
Kit Components	GA213222G1, Tdrd5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213222G2, Tdrd5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213222G3, Tdrd5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001134741, NM_001277730
Synonyms	Gm103
Summary	Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.[UniProtKB/Swiss-Prot Function]

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