Mouse Gnptg activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gnptg
Locus ID	214505
Kit Components	GA213217G1, Gnptg gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213217G2, Gnptg gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213217G3, Gnptg gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001346737, NM_172529
Synonyms	6430527N14Rik; A830081F19; AU067667; AU067744; Mdcp1; Tce7
Summary	Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.[UniProtKB/Swiss-Prot Function]

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