Mouse Tapbpl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tapbpl
Locus ID	213233
Kit Components	GA213134G1, Tapbpl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213134G2, Tapbpl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213134G3, Tapbpl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145391
Synonyms	BC017613; TAPBPL-R; Tapbplr
Summary	Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.[UniProtKB/Swiss-Prot Function]

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