Mouse Dtx4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dtx4
Locus ID	207521
Kit Components	GA212815G1, Dtx4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212815G2, Dtx4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212815G3, Dtx4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172442
Synonyms	AI449438; BC044798; D930042H13; RNF155
Summary	Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4 (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.[UniProtKB/Swiss-Prot Function]

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