Mouse Dtx4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dtx4
Locus ID	207521
Kit Components	GA212815G1, Dtx4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212815G2, Dtx4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212815G3, Dtx4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172442
Synonyms	AI449438; BC044798; D930042H13; RNF155
Summary	Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4 (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.[UniProtKB/Swiss-Prot Function]

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