Mouse Grhl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grhl1
Locus ID	195733
Kit Components	GA212794G1, Grhl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212794G2, Grhl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212794G3, Grhl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161406, NM_145890
Synonyms	LBP-32; MGR; Tcfcp2l2
Summary	Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' (PubMed:18288204, PubMed:21081122). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier (PubMed:18288204, PubMed:24586629). There is no genetic interaction with GRHL3 no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (PubMed:21081122).[UniProtKB/Swiss-Prot Function]

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