Mouse Mbnl3 activation kit by CRISPRa
CAT#: GA212634
Mbnl3 CRISPRa kit - CRISPR gene activation of mouse muscleblind like splicing factor 3
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Mbnl3 |
Locus ID | 171170 |
Kit Components | GA212634G1, Mbnl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212634G2, Mbnl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212634G3, Mbnl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001310515, NM_134163 |
Synonyms | A530038J18Rik; AI661274; CHCR; E430034C16Rik; MBLX; MBLX39; MBXL |
Summary | Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins (By similarity). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN509845 | Mbnl3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |