Mouse Mmaa activation kit by CRISPRa
CAT#: GA212191
Mmaa CRISPRa kit - CRISPR gene activation of mouse methylmalonic aciduria (cobalamin deficiency) type A
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Mmaa |
Locus ID | 109136 |
Kit Components | GA212191G1, Mmaa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212191G2, Mmaa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212191G3, Mmaa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_133823, NM_001363470, NM_001363471, NM_001363472 |
Synonyms | 2810018E08Rik; AI840684 |
Summary | GTPase, binds and hydrolyzes GTP. Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis. Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) and reactivation of the enzyme during catalysis.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN510153 | Mmaa - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |