Mouse Epsti1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Epsti1
Locus ID	108670
Kit Components	GA212122G1, Epsti1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212122G2, Epsti1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212122G3, Epsti1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_029495, NM_178825
Synonyms	2310046K10Rik; 5033415K03Rik; BRESI1
Summary	Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (PubMed:29217193). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (PubMed:29217193).[UniProtKB/Swiss-Prot Function]

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