Mouse Rnf144a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf144a
Locus ID	108089
Kit Components	GA212086G1, Rnf144a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212086G2, Rnf144a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212086G3, Rnf144a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081977, NM_080563
Synonyms	Rnf144; Ubce7ip4; UIP4
Summary	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.[UniProtKB/Swiss-Prot Function]

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