Mouse Adcy3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adcy3
Locus ID	104111
Kit Components	GA211788G1, Adcy3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211788G2, Adcy3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211788G3, Adcy3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001159536, NM_001159537, NM_138305
Synonyms	AC3; mKIAA0511
Summary	Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:9768837, PubMed:11055432, PubMed:25329148). Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis (PubMed:9768837, PubMed:11055432). Required for the perception of odorants (PubMed:11055432). Required for normal sperm motility and normal male fertility (PubMed:15705663). Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (PubMed:25329148).[UniProtKB/Swiss-Prot Function]

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