Mouse Rnf114 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf114
Locus ID	81018
Kit Components	GA211183G1, Rnf114 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211183G2, Rnf114 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211183G3, Rnf114 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_030743, NM_001360930, NR_153838
Synonyms	1110008J21Rik; AI225886; AW549494; Zfp228; Zfp313; Znf228
Summary	E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.[UniProtKB/Swiss-Prot Function]

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