Mouse Wsb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wsb1
Locus ID	78889
Kit Components	GA211057G1, Wsb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211057G2, Wsb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211057G3, Wsb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042565, NM_019653
Synonyms	1110056B13Rik; 2700038M07Rik
Summary	Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]

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