Mouse Arhgap10 activation kit by CRISPRa
CAT#: GA210977
Arhgap10 CRISPRa kit - CRISPR gene activation of mouse Rho GTPase activating protein 10
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Arhgap10 |
Locus ID | 78514 |
Kit Components | GA210977G1, Arhgap10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210977G2, Arhgap10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210977G3, Arhgap10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_030113, NM_001363417, NM_001363418, NM_001363419, NM_001363420, NM_001363421 |
Synonyms | A930033B01Rik; PSGAP-m; PSGAP-s |
Summary | GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN501487 | Arhgap10 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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