Mouse Fbxo31 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo31
Locus ID	76454
Kit Components	GA210513G1, Fbxo31 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210513G2, Fbxo31 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210513G3, Fbxo31 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_133765
Synonyms	1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14
Summary	Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest (By similarity).[UniProtKB/Swiss-Prot Function]

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