Mouse Abcb8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Abcb8
Locus ID	74610
Kit Components	GA209959G1, Abcb8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209959G2, Abcb8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209959G3, Abcb8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029020
Synonyms	4833412N02Rik; AA409895
Summary	ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (By similarity). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (By similarity). Plays a role in mitochondrial iron transport (PubMed:22375032). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (PubMed:22375032).[UniProtKB/Swiss-Prot Function]

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