Mouse Unkl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Unkl
Locus ID	74154
Kit Components	GA209749G1, Unkl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209749G2, Unkl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209749G3, Unkl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001197024, NM_001290736, NM_028789, NM_001357876, NM_001357877
Synonyms	1300004G08Rik
Summary	May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven.[UniProtKB/Swiss-Prot Function]

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