Mouse Vsir activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vsir
Locus ID	74048
Kit Components	GA209691G1, Vsir gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209691G2, Vsir gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209691G3, Vsir gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001159572, NM_028732
Synonyms	4632428N05Rik; Dies1; PD-1H; VISTA
Summary	Immunoregulatory receptor which inhibits the T-cell response (PubMed:21383057, PubMed:24743150, PubMed:25267631). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (PubMed:20042595). May stimulate MMP14-mediated MMP2 activation (By similarity).[UniProtKB/Swiss-Prot Function]

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