Mouse Irak3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irak3
Locus ID	73914
Kit Components	GA209645G1, Irak3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209645G2, Irak3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209645G3, Irak3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_028679, NR_152856, NM_001359184
Synonyms	4833428C18Rik; AI563835; IRAK-M
Summary	Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.[UniProtKB/Swiss-Prot Function]

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