Mouse Hbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hbp1
Locus ID	73389
Kit Components	GA209481G1, Hbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209481G2, Hbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209481G3, Hbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_153198, NM_177993, NM_001361928
Synonyms	1700058O05Rik; BE629963; C86454; C330012F01Rik
Summary	Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).[UniProtKB/Swiss-Prot Function]

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