Mouse Sgip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sgip1
Locus ID	73094
Kit Components	GA209399G1, Sgip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209399G2, Sgip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209399G3, Sgip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001285852, NM_001285859, NM_001285860, NM_001285862, NM_144906
Synonyms	3110007P09Rik; gag; SGIP1alpha
Summary	May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.[UniProtKB/Swiss-Prot Function]

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