Mouse Scn2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Scn2b
Locus ID	72821
Kit Components	GA209346G1, Scn2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209346G2, Scn2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209346G3, Scn2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001014761
Synonyms	2810451E09Rik; AI840361; Gm183
Summary	Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).[UniProtKB/Swiss-Prot Function]

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