Mouse Efhc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Efhc1
Locus ID	71877
Kit Components	GA208992G1, Efhc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208992G2, Efhc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208992G3, Efhc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027974
Synonyms	1700029F22Rik; mRib72-1; myoclonin1
Summary	Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration (By similarity). May enhance calcium influx through CACNA1E and stimulate programmed cell death. Overexpression of EFHC1 in hippocampal primary culture neurons induced apoptosis.[UniProtKB/Swiss-Prot Function]

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