Mouse Spag9 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spag9
Locus ID	70834
Kit Components	GA208634G1, Spag9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208634G2, Spag9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208634G3, Spag9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025428, NM_001025429, NM_001025430, NM_001199203, NM_001199204, NM_001199205, NM_027569, NM_001363157
Synonyms	3110018C07Rik; 4733401I23Rik; 4831406C20Rik; AW552012; Jip4; JLP; JSAP2; JSAP2a
Summary	The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module (PubMed:12391307, PubMed:15767678). Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex (By similarity).[UniProtKB/Swiss-Prot Function]

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