Mouse Gulp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gulp1
Locus ID	70676
Kit Components	GA208594G1, Gulp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208594G2, Gulp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208594G3, Gulp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027506, NM_028450
Synonyms	3110030A04Rik; 5730529O06Rik; CED-6; Ced6; GULP; Gulp-2
Summary	Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization of various LRP1 ligands, such as PSAP (By similarity). May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Increases cellular levels of GTP-bound ARF6.[UniProtKB/Swiss-Prot Function]

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