Mouse Fuz activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fuz
Locus ID	70300
Kit Components	GA208470G1, Fuz gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208470G2, Fuz gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208470G3, Fuz gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_027376
Synonyms	2600013E07Rik; b2b1273Clo
Summary	Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:19877275, PubMed:19767740, PubMed:27158779). May regulate the morphogenesis of hair follicles which depends on functional primary cilia (PubMed:20962855).[UniProtKB/Swiss-Prot Function]

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