Mouse Arap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arap1
Locus ID	69710
Kit Components	GA208290G1, Arap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208290G2, Arap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208290G3, Arap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040111, NM_001040112, NM_027180, NM_198096
Synonyms	2410002L19Rik; Centd2; mKIAA0782
Summary	Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5 (By similarity).[UniProtKB/Swiss-Prot Function]

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