Mouse Chrdl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrdl2
Locus ID	69121
Kit Components	GA208059G1, Chrdl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208059G2, Chrdl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208059G3, Chrdl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291320, NM_133709
Synonyms	1810022C01Rik; Chl2
Summary	Implicated in tumor angiogenesis (By similarity). May inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. May play a role during myoblast and osteoblast differentiation, and maturation.[UniProtKB/Swiss-Prot Function]

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