Mouse Ascc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ascc1
Locus ID	69090
Kit Components	GA208049G1, Ascc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208049G2, Ascc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208049G3, Ascc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199187, NM_026937
Synonyms	1810015P09Rik; AI550520; ASC1p50; CGI-18
Summary	Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction.[UniProtKB/Swiss-Prot Function]

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