Mouse Fbxo32 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo32
Locus ID	67731
Kit Components	GA207483G1, Fbxo32 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207483G2, Fbxo32 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207483G3, Fbxo32 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026346
Synonyms	4833442G10Rik; AI430017; ATROGIN1; Gm20361; MAFbx
Summary	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).[UniProtKB/Swiss-Prot Function]

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