Mouse Hikeshi activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hikeshi
Locus ID	67669
Kit Components	GA207447G1, Hikeshi gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207447G2, Hikeshi gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207447G3, Hikeshi gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291286, NM_001291287, NM_001291288, NM_001291289, NM_026304, NR_111916, NR_153788
Synonyms	0610007P06Rik; 1110002N09Rik; l(7)6Rn; l7Rn6
Summary	Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus (By similarity). May also be indirectly required for organization and/or function of the secretory apparatus in Clara cells in lung.[UniProtKB/Swiss-Prot Function]

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