Mouse Paxbp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Paxbp1
Locus ID	67367
Kit Components	GA207289G1, Paxbp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207289G2, Paxbp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207289G3, Paxbp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026110, NR_152264
Synonyms	1810007M14Rik; C21orf66; Gcfc; Gcfc1; Pax3/7bp
Summary	Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20.[UniProtKB/Swiss-Prot Function]

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