Mouse Ubap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ubap1
Locus ID	67123
Kit Components	GA207153G1, Ubap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207153G2, Ubap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207153G3, Ubap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290454, NM_023305, NM_001355508, NM_001355509
Synonyms	2700092A01Rik; NAG20; Ubap; UBAP-1
Summary	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 (By similarity).[UniProtKB/Swiss-Prot Function]

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