Mouse Cir1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cir1
Locus ID	66935
Kit Components	GA207036G1, Cir1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207036G2, Cir1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207036G3, Cir1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_025854
Synonyms	1700023B02Rik; 2810021A19Rik; Cicr; Cir
Summary	Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription (By similarity). May modulate splice site selection during alternative splicing of pre-mRNAs.[UniProtKB/Swiss-Prot Function]

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