Mouse Pnpla2 activation kit by CRISPRa

CAT#: GA206990

Pnpla2 CRISPRa kit - CRISPR gene activation of mouse patatin-like phospholipase domain containing 2



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Pnpla2
Locus ID 66853
Kit Components

GA206990G1, Pnpla2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206990G2, Pnpla2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206990G3, Pnpla2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001163689, NM_025802, NR_028142
Synonyms 0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2
Summary Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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