Mouse Pnpla2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pnpla2
Locus ID	66853
Kit Components	GA206990G1, Pnpla2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206990G2, Pnpla2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206990G3, Pnpla2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163689, NM_025802, NR_028142
Synonyms	0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2
Summary	Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.[UniProtKB/Swiss-Prot Function]

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