Mouse Mcub activation kit by CRISPRa
CAT#: GA206968
Mcub CRISPRa kit - CRISPR gene activation of mouse mitochondrial calcium uniporter dominant negative beta subunit
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Mcub |
Locus ID | 66815 |
Kit Components | GA206968G1, Mcub gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206968G2, Mcub gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206968G3, Mcub gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001293644, NM_025779 |
Synonyms | 9030408N13Rik; MCUb |
Summary | Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
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CNY 8,680.00 |