Mouse Cntnap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cntnap2
Locus ID	66797
Kit Components	GA206960G1, Cntnap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206960G2, Cntnap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206960G3, Cntnap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001004357, NM_025771
Synonyms	5430425M22Rik; Caspr2; mKIAA0868
Summary	Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons (PubMed:25378149). Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction (Probable) (PubMed:25378149).[UniProtKB/Swiss-Prot Function]

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