Mouse Diablo activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Diablo
Locus ID	66593
Kit Components	GA206857G1, Diablo gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206857G2, Diablo gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206857G3, Diablo gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_023232
Synonyms	0610041G12Rik; 1700006L01Rik; AU040403; Smac
Summary	Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity).[UniProtKB/Swiss-Prot Function]

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