Mouse Htra2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Htra2
Locus ID	64704
Kit Components	GA206490G1, Htra2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206490G2, Htra2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206490G3, Htra2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019752
Synonyms	AI481710; mnd2; Omi; Prss25
Summary	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]

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