Mouse Lat2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lat2
Locus ID	56743
Kit Components	GA206077G1, Lat2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206077G2, Lat2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206077G3, Lat2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020044, NM_022964
Synonyms	AW125574; LAB; NTAL; Wbscr5; Wbscr15; WSCR5
Summary	Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.[UniProtKB/Swiss-Prot Function]

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