Mouse Rabgef1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rabgef1
Locus ID	56715
Kit Components	GA206065G1, Rabgef1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206065G2, Rabgef1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206065G3, Rabgef1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001199059, NM_019983, NM_001359233
Synonyms	Rab5ef; Rabex5; Rin2
Summary	Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A (By similarity). Can act as a ubiquitin ligase (By similarity).[UniProtKB/Swiss-Prot Function]

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