Mouse Rgs19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs19
Locus ID	56470
Kit Components	GA205993G1, Rgs19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205993G2, Rgs19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205993G3, Rgs19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001291205, NM_001291206, NM_001291207, NM_001291208, NM_001291209, NM_001291210, NM_026446
Synonyms	2610042F04Rik; AI324841; AW547781; GAIP
Summary	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity).[UniProtKB/Swiss-Prot Function]

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