Mouse Srcin1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Srcin1
Locus ID	56013
Kit Components	GA205806G1, Srcin1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205806G2, Srcin1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205806G3, Srcin1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018873
Synonyms	mKIAA1684; P140; p140Cap; SNIP
Summary	Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance (By similarity).[UniProtKB/Swiss-Prot Function]

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