Mouse Porcn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Porcn
Locus ID	53627
Kit Components	GA205598G1, Porcn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205598G2, Porcn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205598G3, Porcn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308474, NM_016913, NM_023638, NM_145907, NM_145908, NR_131893
Synonyms	2410004O13Rik; AW045557; DXHXS7465e; Mg61; mMg61; Mporc; porc; Ppn
Summary	Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.[UniProtKB/Swiss-Prot Function]

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