Mouse Snrpa activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Snrpa
Locus ID	53607
Kit Components	GA205582G1, Snrpa gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205582G2, Snrpa gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205582G3, Snrpa gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001046637, NM_001285825, NM_015782
Synonyms	C430021M15Rik; Rnu1a-1; Rnu1a1; U1-A; U1A
Summary	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity).[UniProtKB/Swiss-Prot Function]

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