Mouse Tax1bp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tax1bp1
Locus ID	52440
Kit Components	GA205475G1, Tax1bp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205475G2, Tax1bp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205475G3, Tax1bp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025816, NM_001355595, NM_001355596
Synonyms	1200003J11Rik; 1700069J21Rik; AA930106; D6Ertd404e; D6Ertd772e; T6bp; TXBP151
Summary	Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity).[UniProtKB/Swiss-Prot Function]

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