Mouse Cdca8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdca8
Locus ID	52276
Kit Components	GA205459G1, Cdca8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205459G2, Cdca8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205459G3, Cdca8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026560
Synonyms	4831429J16Rik; AU044747; BOR; Borealin; D4Ertd421e; DasraB; MESRGP
Summary	Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment (By similarity).[UniProtKB/Swiss-Prot Function]

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