Mouse Aass activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aass
Locus ID	30956
Kit Components	GA205307G1, Aass gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205307G2, Aass gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205307G3, Aass gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013930
Synonyms	LKR; LKR/SDH; LOR; LOR/SDH; Lorsdh; SDH
Summary	This gene encodes a bifunctional mitochondrial protein that catalyzes the first two steps in the lysine degradation pathway. The N-terminus contains lysine-ketoglutarate reductase activity and converts lysine to saccharopine, whereas the C-terminus contains saccharopine dehydrogenase activity and converts saccharopine to alpha-aminoadipate semialdehyde. Mutations in a human gene encoding a highly similar protein are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008]

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