Mouse Nelfe activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nelfe
Locus ID	27632
Kit Components	GA205175G1, Nelfe gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205175G2, Nelfe gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205175G3, Nelfe gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001045863, NM_001045864, NM_138580
Synonyms	D17H6S45; NELF-E; RD; Rdbp
Summary	Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity). Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA (By similarity).[UniProtKB/Swiss-Prot Function]

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