Mouse Spry4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spry4
Locus ID	24066
Kit Components	GA204884G1, Spry4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204884G2, Spry4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204884G3, Spry4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011898
Synonyms	A030006O18Rik; sprouty4
Summary	Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras (By similarity). Inhibits Ras-independent, but not Ras-dependent, activation of RAF1 (By similarity).[UniProtKB/Swiss-Prot Function]

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